Tadalafil, sold as Cialis, Tadacip (made by Indian Pharmaceutical company Cipla), Apcalis (Ajanta), Tadalis, Erectalis (Cipla)... and under various other trade names, contains 10mg, 20mg, 100mg tadalafil such as Cialis Professional, Generic Cialis Super Active, Generic Cialis Sublingual, Generic Cialis Soft tab, Generic Cialis Daily, are drugs used to treat erectile dysfunction in men.

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Tadalafil was discovered by Glaxo Wellcome and ICOS, developed and is being marketed by the pharmaceutical giant Lilly ICOS, LLC, the joint venture of ICOS Corporation and Eli Lilly and Company. tadalafil acts by inhibiting cGMP-specific phosphodiesterase type 5 (PDE5), the enzyme that regulates blood flow in the penis.
The dose of tadalafil for erectile dysfunction is 5 mg to 200 mg. In May 2002 tadalafil was proved effective for up to 36 hours. In 2003 it got FDA approval. In 2009, tadalafil was approved for the treatment of pulmonary arterial hypertension under trade name Adcirca in the United States.
Tadalafil's popularity with young man adults has increased over the dedicades. Tadalafil's trade name "Cialis" is widely recognized in US popular culture, and the drug's association with treating erectile dysfunction has led to its recreational use.

The reasons behind such use include the belief that the drug:
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  • Studies on the effects of Cialis when used recreationally are limited, but suggest that it has little effect when used by those not suffering from erectile dysfunction. In one study, a 5 mg dose was shown to cause no significant change in erectile quality, but did reduce the post-ejaculatory refractory time.

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    The primary indication of Brand Cialis is to treat erectile dysfunction (inability to sustain a satisfactory erection to complete intercourse). Cialis use is now standard treatment for erectile dysfunction in all settings, including diabetes.

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